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Cleveland Clinic Mastering the Management of Aortic Valve Disease 2025

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Comprehensive Education in Contemporary Aortic Valve Disease Management

The management of patients with aortic valve disease is rapidly evolving, driven by continuous advances in transcatheter and surgical therapies, imaging technologies, and procedural techniques. In parallel, an expanding body of clinical trials and outcomes research is reshaping evidence-based decision-making across the spectrum of aortic valve disease.

To address these developments, faculty from Cleveland Clinic have designed this educational program, Cleveland Clinic Mastering the Management of Aortic Valve Disease , to provide clinicians with up-to-date clinical evidence, practical management strategies, and multidisciplinary perspectives essential for optimizing outcomes in patients with aortic valve disease.

* Release Date: December 5-6, 2025

LEARNING OBJECTIVES

At the completion of this course, you should be able to:

  • Evaluate the clinical presentation and management strategies for patients with aortic valve disease by integrating patient-specific factors, timing of intervention, and individualized risk stratification.
  • Analyze the strengths, limitations, and appropriate clinical applications of contemporary imaging modalities used in the diagnosis, surveillance, and procedural planning of aortic valve disease.
  • Describe current state-of-the-art and emerging therapeutic options for aortic valve disease, with an emphasis on evidence-based, patient-centered transcatheter and surgical approaches.
  • Apply interprofessional and multidisciplinary strategies to optimize outcomes for patients undergoing transcatheter aortic valve interventions and surgical valve replacement.
  • Navigate complex clinical, ethical, and decision-making challenges in the management of elderly patients and those with significant comorbidities and advanced aortic valve disease.

CLEVELAND CLINIC MASTERING THE MANAGEMENT OF AORTIC VALVE DISEASE 2025

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CLEVELAND CLINIC MASTERING THE MANAGEMENT OF AORTIC VALVE DISEASE 2025 TOPICS

1. Aortic Valve Repair and Root Reimplantation

2. Importance of Prosthesis–Patient Mismatch after TAVR: Definitions, Incidence, and Clinical Relevance

3. Planning for Successful Valve-in-Valve and TAV-in-TAV Procedures

4. Cerebral Embolic Protection During TAVR: What Does the Evidence Support?

5. Optimal Antithrombotic Therapy Post-TAVR: Updates and Controversies

6. Management of Hemodynamic Collapse During TAVR

7. Management of Paravalvular Leaks After SAVR and TAVR

8. Interventional Techniques and Clinical Trials: Preemptive TAVR and Device Durability

9. Aortic Valve Durability: Five- and Seven-Year Results from the COMMENCE Trial

10. Predictors of Pacemaker Dependency Following Aortic Valve Interventions

11. Case Presentation: Cardiogenic Shock Presenting to the Cardiac Intensive Care Unit

12. Acute Valvular Emergencies: Assessment and Stabilization in Cardiogenic Shock

13. Aortic Valve Interventions in Patients with Cardiogenic Shock

14. Aortic Stenosis and Cardiogenic Shock

15. Case Presentation: Radiation Heart Disease with Aortic Valve Involvement

16. Radiation-Associated Cardiovascular Disease: Diagnosis and Management

17. TAVR in Patients with Prior Radiation Therapy

18. Aortic Valve Disease Associated with Radiation: Surgical Options

19. Case Presentation: Young Patient with Connective Tissue Disorder (Marfan Syndrome vs Loeys–Dietz Syndrome)

20. Screening and Management of High-Risk Patients with Heritable Thoracic Aortic Disease

21. Surgical Management of the Aortic Root

22. Cleveland Clinic Contributions to TAVR: Key Advances in 2025

23. Case Presentation: Patient with Severe Aortic Insufficiency

24. Aortic Regurgitation: Multimodality Imaging Work-Up and Guideline-Based Management

25. Treatment of Aortic Insufficiency Using TAVR Systems: Current Landscape in 2025

26. Most Influential TAVR Publications from 2024–2025

27. Landmark Cleveland Clinic Surgical Papers in Aortic Valve Disease

28. Clinical Information and Long-Term Management Beyond the Index Procedure

29. Medical Therapy for Aortic Stenosis: Emerging Evidence and Clinical Practice

30. Managing Heart Failure in Aortic Stenosis with Multivalvular Disease

31. Aortic Stenosis and Heart Failure

32. Multimodality Imaging in Aortic Valve Disease: The Imaging Cardiologist’s Perspective

33. Benefit of Surgical Intervention in Low-Flow, Low-Gradient Severe Aortic Stenosis

34. Case Presentation: Aortic Valve Endocarditis

35. Role of Multimodality Imaging in Aortic Valve Endocarditis

36. Critical Care Management in Aortic Valve Endocarditis

37. Surgical Options for Aortic Valve Endocarditis

38. Case Presentation: Low-Risk Aortic Stenosis

39. Case Presentation: Low-Flow, Low-Gradient Aortic Stenosis

40. Case Presentation: Stenotic Bicuspid Aortic Valve in an Octogenarian

41. Aortic Stenosis in the Elderly: Frailty, Imaging, and Futility Assessment

42. Association of Bicuspid Aortic Valve Anatomy with TAVR Outcomes

43. Contemporary Surgical Outcomes and the Role of Surgery in Aortic Valve Disease

44. Assessing Flow Reserve, Aortic Valve Calcium Score, and Team-Based Care

45. TAVR for Low-Flow, Low-Gradient Severe Aortic Stenosis: State-of-the-Art Review

46. Surgical Perspective: Current Evidence Supporting SAVR

47. Interventional Perspective: Evidence Supporting Low-Risk TAVR Trials

48. Contemporary Trends in Aortic Valve Disease Management

49. Sex Differences in Aortic Valve Disease: Clinical Implications

50. Evaluation of Procedural Risk and Shared Decision-Making in Aortic Valve Disease

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