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Harvard Advances in Cytology and Small Biopsies 2025

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State-of-the-Art Diagnostic Pathology CME

Advances in Cytology and Small Biopsies — hosted by Harvard Medical School, provides pathologists and cytotechnologists with a comprehensive overview of diagnostic pathology utilizing both cytology and small biopsy specimens. The conference emphasizes the integration of light microscopy with ancillary testing like immunocytochemistry, biochemical testing, and genetic analysis for diagnosis, prognosis, and targeted therapy. It also covers advancements in automation, standardized terminology, and quality assurance. The conference features lectures, Q&A sessions, and case-based presentations, with an optional “sign out with the faculty” session for hands-on experience.

* Date of Original Release: June 9-11, 2025

LEARNING OBJECTIVES

At the conclusion of this activity, the participant will be able to:

  • Recognize the full range of diagnostic approaches to cytological and small tissue samples from all body sites
  • Evaluate current and potential applications of automated screening, liquid-based preparation methods, flow cytometry and molecular testing
  • Assess the impact of new technologies on cytology practice
  • Apply current standards for the evaluation and work-up of cytology and small tissue samples for diagnosis, prognosis and targeted therapy
  • Summarize the new standardized terminology and reporting systems for gynecological, pancreaticobiliary, thyroid, salivary gland and urinary cytological specimens
  • Identify diagnostic pitfalls and how to avoid them

HARVARD ADVANCES IN CYTOLOGY AND SMALL BIOPSIES 2025

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HARVARD ADVANCES IN CYTOLOGY AND SMALL BIOPSIES 2025 TOPICS

1. HSIL and Its Mimics – Vanda Torous, MD

2. Endocervical-AGCs and Worse – Vanda Torous, MD

3. Endometrial Cells and Their Mimics – Jeffrey Mito, MD, PhD

4. Day 1 Question 1 – Jeffrey Mito, MD, PhD; Vanda Torous, MD

5. Primary HPV Screening and Management of Abnormal Screening Results – Stephanie Alimena, MD

6. Integrating Primary HPV Screening into the Cytology Laboratory – Jeffrey Mito, MD, PhD

7. Day 1 Question 2 – Jeffrey Mito, MD, PhD; Stephanie Alimena, MD

8. Updates in Anal Cytology – Hannah Chen, MD, PhD

9. Clinical Management of Patients with Anal Dysplasia – Benjamin Davis, MD

10. Day 1 Question 3 – Ivan Chebib, MD, FRCPC

11. Automation and Artificial Intelligence in Cytology – Emilio Madrigal, DO

12. Lymph Node FNA – Amy Ly, MD

13. Day 1 Question 4 – Amy Ly, MD; Emilio Madrigal, DO

14. Challenging Cases and Lessons Learned: Virtual Microscopy 1 – Sarah Wu, MD, PhD; Jeffrey Mito, MD, PhD; Melanie Kwan, MD

1. Refining the Diagnosis: Evolving Concepts in Urinary Tract Cytopathology – Christopher VandenBussche, MD, PhD

2. Malignant Effusions: Primary versus Metastatic – Marina Vivero, MD

3. Pulmonary Cytology: Workup of NSCLC on FNA and Small Biopsy – Paul VanderLaan, MD, PhD

4. Molecular Testing in Cytology Specimens – Lynette Sholl, MD

5. Day 2 Question 1 – Jeffrey Mito, MD, PhD

6. Update on WHO Reporting Systems – Martha Bishop Pitman, MD

7. Soft Tissue FNA and Small Biopsy: Part 1 – Ivan Chebib, MD

8. Soft Tissue FNA and Small Biopsy: Part 2 – Vickie Jo, MD

9. Day 2 Question 2 – Ivan Chebib, MD, FRCPC; Vickie Jo, MD

10. Challenging Cases and Lessons Learned: Virtual Microscopy 2 – Amy Ly, MD; Ruhani Sardana, MD; Mohammad Al-Attar, MD

10b. Challenges and Lessons Learned: Virtual Microscopy 2 – Mohammad M. Al-Attar, MD

1. The Atypical Thyroid Aspirate – Edmund Cibas, MD

2. Laboratory Quality Assurance Through the Lens of the Bethesda System – Paul VanderLaan, MD, PhD

3. Day 3 Question 1 – Jeffrey Mito, MD, PhD

4. Challenging Head and Neck Biopsies – Kristine Wong, MD

5. Molecular Testing in Thyroid FNAs – Michiya Nishino, MD, PhD

6. Salivary Gland Cytology and the Milan System – William Faquin, MD, PhD

7. HPV Testing in H&N Squamous Cell Carcinoma – William Faquin, MD, PhD

8. Day 3 Question 2 – Ivan Chebib, MD, FRCPC; William Faquin, MD, PhD

9. Pancreatic Ductal Carcinoma – Lisa Zhang, MD

10. Non-Ductal Neoplasms of the Pancreas – Lisa Zhang, MD

11. Pancreatic Cysts – Martha Bishop Pitman, MD

12. Day 3 Question 3 – Ivan Chebib, MD, FRCPC

13. Challenges and Lessons Learned: Virtual Microscopy 3 – Ivan Chebib, MD, FRCPC; Melissa Zhao, MD, MS

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