Harvard Molecular Diagnostics: Current Roles in Cancer Diagnosis and Patient Management

1. Course Introduction

2. Introduction to Molecular Diagnostics – Fei Dong, MD

3. Specimen Handling for Molecular Success – Lynette Sholl, MD

4. An Introduction to Cytogenetic Techniques – Azra Ligon, PhD

5. Question and Answer – Fei Dong, MD; Azra Ligon, PhD; Lynette Sholl, MD

6. An Introduction to Next Generation Sequencing – Laura Macconaill, PhD

7. An Introduction to Bioinformatic Pipelines for NGS – Ryan Schmidt, MD, PhD

8. Question and Answer – Laura Macconaill, PhD; Ryan Schmidt, MD, PhD

9. An Introduction to Liquid Biopsy (Cell Free DNA Sequencing) – Technical Topics – Long Phi Le, MD, PhD

10. An Introduction to Liquid Biopsy (Cell Free DNA Sequencing) – Clinical Applications – Giulia Siravegna, PhD

11. Tumor Mutation Burden and Microsatellite Instability Testing – Jonathan Nowak, MD, PhD

12. Question and Answer – Long Phi Le, MD, PhD; Jonathan Nowak, MD, PhD

13. Live Advanced Workshop: Informatics – Long Phi Le, MD, PhD

1. Molecular Diagnostics for Breast Cancer – Deborah Dillon, MD

2. Molecular Diagnostics of Gynecologic Tumors – Lauren Ritterhouse, MD, PhD

3. Question and Answer – Lynette Sholl, MD; Deborah Dillon, MD; Lauren Ritterhouse, MD, PhD

4. Molecular Diagnostics of Melanoma – Ryan Sullivan, MD

5. Molecular Diagnostics of Pediatric and Rare Tumors – Alanna Church, MD

6. Question and Answer

7. Metastatic Inflammatory Myofibroblastic Tumor – Alanna Church, MD

8. Clinical Interpretation of Sequence and Copy Number Variants (Cancer NGS) – Fei Dong, MD

9. Clinical Interpretation for Gene Fusions – Valentina Nardi, MD

10. Clinical Interpretation of Germline Cancer Predisposition – Diana Mandelker, MD, PhD

11. Question and Answer

12. Live Advanced Workshop: Fusion Interpretation – Adam Fisch, MD, PhD

1. Hot Topics in Measurable (Minimal) Residual Disease Testing – Annette S. Kim, MD, PhD

2. Hot Topics in Myeloid Neoplasms – Valentina Nardi, MD

3. Targetable Fusions in Acute Lymphoblastic Leukemia – Marian Harris, MD, PhD

4. Question & Answer – Lynette Sholl, MD; Marian Harris, MD, PhD; Valentina Nardi, MD; Annette S. Kim, MD, PhD

5. Molecular Diagnostics for B-cell Lymphomas – Scott B. Lovitch, MD, PhD

6. Molecular Diagnostics for T-cell Lymphomas – David Weinstock, MD

7. Hematological Malignancy Case Presentation – Hanno Hock, MD, PhD and Valentina Nardi, MD

8. Question & Answer

9. Molecular Diagnostics for Sarcomas – Adrian Marino-Enriquez, MD, PhD

10. Molecular Diagnostics for Gliomas – David Meredith, MD, PhD

11. Clinical Applications of Whole Genome DNA Methylation Profiling – Matija Snuderl, MD

12. Question & Answer – Valentina Nardi, MD; Adrian Marino-Enriquez, MD, PhD; David Meredith, MD, PhD; Matija Snuderl, MD

13. Live Advanced Workshop: Copy Number by Microarray & NGS – Adrian Dubuc, PhD

1. Molecular Diagnostics for Lung Cancer – Lynette Sholl, MD

2. Molecular Diagnostics for Thyroid Cancer – Dora Dias-Santagata, PhD, FACMG

3. Question & Answer – Alanna Church, MD; Dora Dias-Santagata, PhD, FACMG; Lynette Sholl, MD

4. Molecular Biomarkers for GU Cancers – Atish Choudhury, MD, PhD

5. Molecular Diagnostics for GI Cancers – Jonathan Nowak, MD, PhD

6. Clinical Case Presentation and Discussion – Lung Tumor – Mark Awad, MD, PhD

7. Question & Answer – Alanna Church, MD; Mark Awad, MD, PhD; Atish Choudhury, MD, PhD; Lynette Sholl, MD; Jonathan Nowak, MD, PhD

8. Billing and Regulatory Issues – Jochen K. Lennerz, MD, PhD

9. Opportunities in Molecular Lab Management – Neal Lindeman, MD

10. Clinical Trials and Regulatory Affairs – Hetal Marble, PhD

11. Question & Answer – Alanna Church, MD; Aaron Lafrate, MD; Jochen K. Lennerz, MD, PhD

12. Wrap up and Thank You – Alanna Church, MD; Valentina Nardi, MD; Lynette Sholl, MD