PIXORIZE USMLE BIOCHEMISTRY OUTLINE 2022
1. Vitamins (23)
1. Vitamin B1 (Thiamine) Biochemistry
2. Vitamin B1 (Thiamine) Deficiency
3. Vitamin B2 (Riboflavin)
4. Vitamin B3 (Niacin) Biochemistry
5. Vitamin B3 (Niacin) Deficiency and Excess
6. Hartnup Disease
7. Vitamin B5 (Pantothenic Acid)
8. Vitamin B6 (Pyridoxine)
9. Vitamin B7 (Biotin)
10. Vitamin B9 (Folate)
11. Vitamin B12 (Cobalamin) Biochemistry
12. Vitamin B9 & B12 Deficiencies
13. Vitamin A (Retinol) Biochemistry
14. Vitamin A (Retinol) Deficiency and Excess
15. Vitamin C (Ascorbic Acid) Biochemistry
16. Vitamin C (Ascorbic Acid) Deficiency and Excess
17. Vitamin D Biochemistry
18. Vitamin D Deficiency and Excess
19. Vitamin E (Tocopherol/Tocotrienol)
20. Vitamin K Biochemistry
21. Vitamin K Deficiency
22. Zinc
23. Kwashiorkor and Marasmus
2. Biochemical Pathways (23)
1. Glycolysis
2. Citric Acid Cycle (TCA Cycle)
3. Electron Transport Chain (ETC)
4. Cori Cycle
5. De Novo Purine Synthesis
6. De Novo Pyrimidine Synthesis
7. Purine Salvage
8. Purine Excretion
9. Ethanol Metabolism
10. Pyruvate Metabolism
11. HMP Shunt (Pentose Phosphate Pathway)
12. Galactose Metabolism
13. Sorbitol (Polyol) Pathway
14. Urea Cycle
15. Alanine (Cahill) Cycle
16. Catecholamine Synthesis & Breakdown
17. Homocysteine Metabolism
18. Fatty Acid Synthesis (Citrate Shuttle)
19. Fatty Acid Breakdown (Carnitine Shuttle)
20. Propionic Acid Pathway
21. Fructose Metabolism
22. Regulation by Fructose-2,6-Bisphosphate (F-2,6-BP)
23. Glycogenesis
3. Metabolic Disorders (19)
1. Albinism
2. Pyruvate Dehydrogenase Deficiency
3. Pyruvate Kinase Deficiency
4. G6PD Deficiency
5. Essential Fructosuria
6. Hereditary Fructose Intolerance
7. Galactosemia
8. Galactokinase Deficiency
9. Lactase Deficiency
10. Ornithine Transcarbamylase Deficiency
11. Phenylketonuria
12. Maple Syrup Urine Disease (MSUD)
13. Alkaptonuria
14. Homocystinuria
15. Cystinuria
16. Propionic Acidemia
17. Lesch-Nyhan Syndrome
18. Systemic Primary Carnitine Deficiency
19. MCAD Deficiency
4. Lipid (8)
1. Chylomicron Metabolism
2. VLDL Metabolism
3. HDL Metabolism
4. Abetalipoproteinemia
5. Familial Hyperchylomicronemia
6. Familial Hypercholesterolemia
7. Familial Dysbetalipoproteinemia
8. Familial Hypertriglyceridemia
6. Autosomal Dominant Diseases (13)
1. Marfan Syndrome
2. Li-Fraumeni Syndrome (LFS)
3. Achondroplasia
4. Job (Hyper IgE) Syndrome
5. HHT
6. Hereditary Spherocytosis
7. von Hippel-Lindau (VHL)
8. MEN 1
9. MEN 2
10. von Recklinghausen Disease (NF-1)
11. Neurofibromatosis Type II (NF 2)
12. Myotonic Dystrophy
13. ADPKD
7. Lysosomal Storage Diseases (7)
1. Krabbe Disease
2. Hurler and Hunter Syndromes
3. Fabry Disease
4. Tay-Sachs and Niemann-Pick
5. Gaucher Disease
6. Metachromatic Leukodystrophy
7. I-Cell Disease
9. Chromosomal Abnormalities (8)
1. Down Syndrome (Trisomy 21)
2. Edward Syndrome (Trisomy 18)
3. Patau (Trisomy 13)
4. Klinefelter Syndrome
5. Turner Syndrome
6. Williams Syndrome
7. Cri du Chat Syndrome
8. Imprinting
10. Collagen-Related Disorders (6)
1. Alport Syndrome
2. Menkes Disease
3. Osteogenesis Imperfecta (Brittle Bone Disease)
4. Collagen Synthesis
5. Ehlers-Danlos Syndrome
6. Goodpasture Syndrome
11. DNA Repair (4)
1. Lynch Syndrome (HNPCC)
2. Xeroderma Pigmentosum
3. Ataxia-Telangiectasia
4. Bloom Syndrome
12. Lung Cancer (6)
1. Lung Cancer Overview
2. Small Cell Carcinoma
3. Adenocarcinoma
4. Squamous Cell Carcinoma
5. Large Cell Carcinoma
6. Bronchial Carcinoid Tumor
13. Toxicology (7)
1. Cyanide Poisoning
2. Tetrodotoxin
3. Methanol Poisoning
4. Ethylene Glycol Poisoning
5. Ciguatoxin (Ciguatera Fish Poisoning)
6. Spoiled Fish (Scombroid) Poisoning
7. Carbon Monoxide Poisoning
14. Mechanoreceptors (4)
1. Pacinian Corpuscle (Lamellar Corpuscle)
2. Meissner Corpuscle (Tactile Corpuscle)
3. Merkel Disk
4. Ruffini Endings (Ruffini Corpuscle)
15. Vasculitides (9)
1. Giant Cell (Temporal) Arteritis
2. Henoch-Schonlein Purpura
3. Takayasu Arteritis
4. Buerger’s Disease (Thromboangiitis Obliterans)
5. Behcet Disease
6. Granulomatosis with Polyangiitis
7. Mixed Cryoglobulinemia
8. Microscopic Polyangiitis
9. Kawasaki Disease
20. Misc (17)
1. Osteosarcoma
2. McCune-Albright Syndromes
3. Hexokinase vs Glucokinase
4. COP I, COP III, and Clathrin
5. Kartagener Syndrome (Primary Ciliary Dyskinesia)
6. Familial Adenomatous Polyposis (FAP)
7. Peutz-Jegher Syndrome
8. Cystic Fibrosis Overview
9. Cystic Fibrosis Complications
10. Medicare vs. Medicaid
11. Duchenne & Becker Muscular Dystrophy
12. Yolk Sac Tumor
13. Rett Syndrome
14. Fragile X Syndrome
15. Whipple’s Disease
16. Osteoid Osteoma vs Osteoblastoma
17. T1 vs T2 MRI