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2026 Pathology Review: Practical Updates in Hematolymphoid, Genitourinary, and Orthopedic Pathology for the General Pathologist

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Practical Updates in Hematolymphoid, Genitourinary, and Orthopedic Pathology

This CME teaching activity has been designed to provide an overview of some of the most common areas of diagnostic difficulty encountered by practicing pathologists in the areas of hematolymphoid, genitourinary, and orthopedic pathology. 2026 Pathology Review: Practical Updates in Hematolymphoid, Genitourinary, and Orthopedic Pathology for the General Pathologist delivers practical, case-oriented teaching focused on real-world diagnostic challenges commonly faced in daily pathology practice.

The course provides extensive details of some of the most important diagnostic features that allow pathologists to make accurate diagnoses in each of these subspecialized areas, while emphasizing how to assess essential diagnostic clues and avoid common diagnostic pitfalls. Lectures also include discussions on ancillary diagnostic techniques such as immunohistochemistry and molecular pathology, with selected sessions incorporating case-based learning for enhanced clinical application.

* Date of Original Release: May 1, 2026

LEARNING OBJECTIVES

At the completion of this CME teaching activity, you should be able to:

  • Recognize the most common issues related to pathology of arthroplasty specimens
  • Define non-neoplastic and neoplastic diseases of the synovium
  • Become more comfortable handling frozen sections in the diagnosis of periprosthetic joint infection
  • Review the most common non-neoplastic musculoskeletal lesions encountered by general surgical pathologists
  • Identify the diagnostic features of benign and malignant hyaline cartilage neoplasms
  • List the most common giant cell-rich bone neoplasms and approaches to their diagnosis
  • Recognize the most common benign mimickers of prostate cancer
  • Identify prostatic lesions with cribriform architecture, both benign and malignant
  • Recognize flat and deceptively bland urothelial lesions, as well as papillary urothelial lesions
  • List the most common renal neoplasms with clear cytoplasm and those with eosinophilic/pink cytoplasm
  • Discuss an approach to CBC abnormalities in both adults and children
  • Recognize the most common forms of myelodysplasia and other myeloid neoplasms
  • Review the essential diagnostic features of acute myeloid leukemia
  • Discuss approaches to diagnosing lymphoid disorders in bone marrow and peripheral blood
  • Recognize common entities of B-lymphoid and T/NK neoplasms in blood and bone marrow

2026 PATHOLOGY REVIEW: PRACTICAL UPDATES IN HEMATOLYMPHOID, GENITOURINARY, AND ORTHOPEDIC PATHOLOGY FOR THE GENERAL PATHOLOGIST

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2026 PATHOLOGY REVIEW: HEMATOLYMPHOID, GENITOURINARY & ORTHOPEDIC PATHOLOGY TOPICS

1. Benign Mimickers of Prostate Cancer – Cristina Magi-Galluzzi, M.D., Ph.D.

2. Common and Uncommon Prostatic Lesions with Cribriform Architecture – Cristina Magi-Galluzzi, M.D., Ph.D.

3. Flat and Deceptively Bland Urothelial Lesions: Nothing to Be Trifled With! – Cristina Magi-Galluzzi, M.D., Ph.D.

4. Papillary Urothelial Lesions – Cristina Magi-Galluzzi, M.D., Ph.D.

5. Renal Tumors with Clear Cytoplasm – Cristina Magi-Galluzzi, M.D., Ph.D.

6. Pink Renal Tumors: How Far Can You Go with Morphology? – Cristina Magi-Galluzzi, M.D., Ph.D.

7. What Matters Is Not Easy: Pitfalls & Challenges in GU Pathology – Cristina Magi-Galluzzi, M.D., Ph.D.

1. Approach to CBC Abnormalities in Children and Adults – Kathryn Foucar, M.D.

2. Does My Patient Have Myelodysplasia or Some Other Myeloid Neoplasm? – Kathryn Foucar, M.D.

3. Acute Myeloid Leukemia: Journey from Blast Percentages to Next Generation Sequencing – Kathryn Foucar, M.D.

4. Exemplary Myeloid Disorder Cases – Kathryn Foucar, M.D.

5. Approach to Lymphoid Disorders in Blood and Bone Marrow – Kathryn Foucar, M.D.

6. B-Lymphoid Neoplasms in Blood and Bone Marrow – Kathryn Foucar, M.D.

7. T/NK-Neoplasms in Blood and Bone Marrow – Kathryn Foucar, M.D.

1. The Pathologist’s Role in the Diagnosis of Periprosthetic Joint Infection – John Reith, M.D.

2. Non-Neoplastic Musculoskeletal Lesions Every General Surgical Pathologist Should Recognize – John Reith, M.D.

3. Practical Arthroplasty Pathology – John Reith, M.D.

4. Hyaline Cartilage Neoplasms – Radiology to the Rescue! – John Reith, M.D.

5. Synovial Pathology – John Reith, M.D.

6. Giant Cell-Rich Bone Neoplasms – How to Solve the Mystery – John Reith, M.D.

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