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KAPLAN USMLE Step 1 Prep 2018

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KAPLAN USMLE® Step 1 Prep — USMLE prep created and taught by board-certified medical professionals who know what it takes to reach your residency!

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KAPLAN STEP 1 - ON DEMAND 2018 OUTLINE

1. Anatomy - David Seiden, Jim White

Basal Ganglia

1

Basal Ganglia

2

Basal Ganglia Pathways

3

Basal Ganglia Structures

4

Diseases of the Basal Ganglia

Cerebral Cortex

1

Cerebral Cortex Right Hemisphere

2

Blood Supply of the Brain

3

Cerebrovascular Disorders

4

Cerebral Cortex Left Hemisphere

5

Clinical Correlates Part 1

6

Clinical Correlates Part 2

7

CNS Blood Supply and Stroke Related Deficits

8

Key Features of Lobes

Diencephalon

1

Diencephalon

2

Thalamus

3

Hypothalamus

4

Epithalamus

Histology of the Nervous System

1

Histology of the Nervous System

2

Axonal transport

3

Glial and Supporting Cells

4

Conditions of Impaired Myelination

5

Histology of the Peripheral Nervous System

6

Blood Brain Barrier

7

Axotomy, Chromatolysis, and Regeneration

8

Primary Tumors

Limbic System

1

Limbic System

Nervous System Organization and Development

1

Nervous System Organization and Development

2

Congenital Malformations of the Nervous System

3

Germ Layer Derivatives Ectoderm

4

Autonomic Nervous System General Organization

5

Parasympathetic and Sympathetic Outflow

6

Cross Section of Spinal Cord

The Brain Stem

1

The Brain Stem

2

Upper Midbrain

3

Lower Midbrain

4

Middle Pons

5

Lower Pons

6

Medulla

7

Cranial Nerves I And II

8

Cranial Nerves III, IV, And VI

9

Cranial Nerve V, VII and VIII

10

Cranial Nerves IX, X, XI and XII

11

Trigeminal nuclei

12

Corticobulbar (Corticonuclear) Innervation of Cranial Nerve Nuclei

13

Components Of The Ear, Auditory, And Vestibular System

14

Auditory System

15

Vestibular System

16

Caloric Test

17

Horizontal Conjugate Gaze

18

Blood Supply To The Brain Stem

19

Medullary Lesions

20

Pons Lesions

21

Midbrain Lesions

22

Strategy for the Study of Lesions

The Cerebellum

1

The Cerebellum

2

Cerebellar Cytoarchitecture

3

Circuitry

4

Cerebellar Lesions

The Spinal Cord

1

The Spinal Cord General Features

2

Dorsal Horn

3

Ventral Horn

4

Neural Systems Introduction

5

Motor System

6

Commonly Tested Muscle Stretch Reflexes

7

UMN vs LMN Lesions

8

Sensory Systems

9

Spinocerebellar Pathways

10

Spinal Cord Levels and Pathways

11

Brown-Se´quard Syndrome

12

Lesions of the Spinal Cord I

13

Lesions of the Spinal Cord II

Ventricular System

1

Ventricular System

Visual Pathways

1

Visual Pathways

2

Visual Reflexes

3

Clinical Correlates Pupillary Abnormalities

4

Eyeball And Optic Nerve

5

Visual Field Defects

2. Behavioral Science - Alina Gonzalez-Mayo

1. Substance Abuse

1

Physiology of Substance Abuse

2

Alcohol and Alcoholism

3

Common Abused Substances

4

Other Abused Substances

5

Substance-Abusing Physicians

2. Human Sexuality

1

Sexual Behavior in the United States

2

Paraphilias

3

Sexual Dysfunctions

4

Masturbation

5

Homosexuality

6

Sexuality and Aging

3. Learning and Behavior Modification

1

Learning and Behavior

2

Behavior Therapy and Behavior Modification

4. Defense Mechanisms

1

General Issues

2

Four Clusters of Defenses

3

Transference

5. Psychologic Health and Testing

1

Psychologic Health and Physical Health

2

Psychologic Adjustment and Physical Health

3

Intelligence Q

4

Personality Tests

5

Neuropsychologic Test

6. Human Development

1

Developmental Milestones

2

Applying Child-Development Principles

3

Abuse

7. Sleep and Sleep Disorders

1

Sleep Architecture

2

Developmental Aspects of Sleep

3

Sleep Disorders

4

Biochemistry of Sleep

8. Physician-Patient Relationships

1

General Rules about Physician-Patient Relationships

9. Diagnostic and Statistical Manual (DSMV)

1

Childhood Disorders

2

Schizophrenia

3

Mood Disorderss

4

Eating and Anxiety Disorders

5

Obsessive Compulsive and Related Disorders

6

Personality Disorders

10. Organic Disorders

1

Tourette Syndrome

2

HIV-Related Dementia

3

Delirium versus Dementia

4

Hemispheric Dominance

5

Brain and Behavior

11. Psychopharmacology

1

Antipsychotics (Neuroleptics)

2

Antidepressants

3

Mood Stabilizers

4

Anxiolytics (Antianxiety)

12. Ethical and Legal Issues

1

Legal Issues Related to Medical Practice

3. Biochemistry - Sam Turco, David Seastone

1. Nucleic Acid Structure and Organization

1

Overview The Central Dogma of Molecular Biology

2

Nucleotide Structure and Nomenclature

3

Nucleic Acids

4

Organization of DNA

2. DNA Replication and Repair

1

Overview of DNA Replication

2

Comparison of DNA and RNA Synthesis

3

Steps of DNA Replication

4

DNA Repair

3. Transcription and RNA Processing

1

Overview of Transcription

2

RNA Polymerases

3

Transcription Important Concepts and Terminology

4

Production of Prokaryotic Messenger RNA

5

Production of Eukaryotic Messenger RNA

6

Alternative Splicing-Eukaryotic Primary Pre-mRNA Transcripts

7

Ribosomal RNA (rRNA) Is Used to Construct Ribosomes

8

Transfer RNA Carries Activated Amino Acids for Translation

4. The Genetic Code, Mutations, and Translation

1

Overview of Translation

2

Mutations

3

Amino Acid Activation and Codon Translation by tRNAs

4

Translation (Protein Synthesis)

5

Inhibitors of Protein Synthesis

6

Protein Folding and Subunit Assembly

7

Translation Occurs on Free Ribosomes and on the RER

8

Co- and Posttranslational Covalent Modifications

9

Posttranslational Modifications of Collagen

5. Regulation of Eukaryotic Gene Expression

1

Overview of Genetic Regulation

2

Regulation of Eukaryotic Gene Expression

6. Genetic Strategies in Therapeutics

1

Overview of Recombinant DNA Technology

2

Human Genome Project and Cloning Genes

3

Medical Application of Recombinant DNA

4

RNA Interference

7. Techniques of Genetic Analysis

1

Blotting Techniques

2

Polymerase Chain Reaction (PCR)

8. Amino Acids, Proteins, and Enzymes

1

Amino Acids

2

Protein Turnover

3

Biochemical Reactions

9. Hormones

1

Hormones and Signal Transduction

2

Water-Soluble Hormones Mechanism

3

G-Proteins in Signal Transduction

4

Lipid Soluble Hormones

10. Vitamins

1

Water Soluble Vitamins

2

Lipid Soluble Vitamins

1

Abetalipoproteinemia

2

Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

3

Li-Fraumeni

4

Sickle Cell Disease

5

Fatty Acid Oxidation

Immunology - Kim Moscatello-Seastone

Medical Genetics - Vernon Reichenbacher

Microbiology - Kim Moscatello-Seastone

6. Medical Genetics – Vernon Reichenbacher

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